Biotin is one of a handful of B vitamins that is specifically responsible for the catalysis of glucose, fatty acids, and amino acids that are converted into energy. Its water solubility makes it a crucial cofactor for five carboxylases namely acetyl-CoA carboxylase 2, pyruvate carboxylase, acetyl-CoA carboxylase 1, methylcrotonyl-CoA carboxylase, and propionyl-CoA carboxylase. Besides that, it helps in cell signalling, histone modifications and gene regulation. In gene regulation, it acts by positively altering the factors of transcription.
February 21, 2020